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Biopsy & Treatments of Lesions of Vulva & Vagina

Biopsy and treatment of lesions on the vulva and vagina are critical procedures for diagnosing and managing abnormalities such as suspicious growths, ulcers, or discolorations. These procedures help identify benign conditions, infections, precancerous changes, or malignancies and guide appropriate treatment strategies.

Biopsy of Vulvar and Vaginal Lesions

When Is a Biopsy Needed?

A biopsy is recommended for:

  • Persistent or suspicious lesions (e.g., discolorations, lumps, or sores).
  • Non-healing ulcers or chronic irritation.
  • Lesions associated with pain, itching, or bleeding.
  • Areas suspected of precancerous or cancerous changes (e.g., vulvar intraepithelial neoplasia, VIN).

Types of Biopsies

1. Punch Biopsy

  • Removes a small, round sample of tissue using a punch tool.
  • Ideal for diagnosing small lesions or obtaining a portion of larger lesions.

2. Excisional Biopsy

  • Removes the entire lesion or growth, typically when malignancy is suspected.
  • Also serves as a treatment if the lesion is benign.

3. Incisional Biopsy

  • Removes a portion of a larger lesion for diagnostic purposes.

4. Shave Biopsy

  • A superficial technique to remove the upper layers of the lesion, often for benign conditions.

Treatment of Lesions

Common Lesions and Their Treatments

1. Benign Lesions (e.g., cysts, skin tags)

  • Treatment: Excision, laser therapy, or cryotherapy.

2. Bartholin's Gland Cysts or Abscesses

  • Treatment: Incision and drainage, marsupialization, or gland removal in recurrent cases.

3. Genital Warts (HPV-related)

  • Treatment: Cryotherapy, laser ablation, topical treatments (e.g., imiquimod), or excision.

4. Lichen Sclerosus or Lichen Planus

  • Treatment: High-potency corticosteroids or immunosuppressive creams.

5. Precancerous Lesions (e.g., VIN)

  • Treatment: Laser ablation, excision, or topical medications like imiquimod.

6. Malignant Lesions (e.g., vulvar or vaginal cancer)

  • Treatment: Surgical excision (local or radical), radiation, or chemotherapy, depending on the stage.

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